Liver Transplantation Can Cure Liver Cancer: What we need to know

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The most common type of liver cancer in Singapore is primary liver cancer, specifically hepatocellular carcinoma (HCC). This is a type of cancer which originates from liver cells. According to data from a 2012 report of the World Health Organization (WHO), there were 782,000 new cases per year of liver cancer worldwide. It is the […]

Liver Disease 101: Is my liver abnormal?

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The liver is an important organ situated in the upper part of the abdomen. It has several functions. It is responsible for manufacturing many proteins required for the normal functioning of the body (e.g. proteins which enable our blood to clot when we have a cut). It manufactures bile which is important in fat digestion. […]

Pancreatic Cystic Lesions – Understanding the condition and treatment management options

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Pancreatic cystic lesions are being identified with increasing frequency. They range from inflammatory or benign types to precancerous or frankly malignant lesions. Most of these cysts are asymptomatic and are incidental findings due to the growing use of cross-sectional imaging. Pancreatic cysts may be classified into inflammatory non-neoplastic pseudocysts or true pancreatic cystic neoplasms (PCNs) […]

Liver Transplantation

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Liver transplantation is an important treatment option for patients with chronic liver disease, acute liver failure and primary liver cancer. The first successful liver transplantation in humans was performed by Thomas Starlz in 1967. Since then, the field of transplantation has expanded due to improvements in surgical techniques, peri-operative management, preservation solution and immunosuppression regimens. […]

A Passion for Surgery

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It is not often that someone tells you that every single day on the job is a career highlight, but those are the words of Dr Cheah Yee Lee, a surgeon specialising in liver transplant and hepatopancreatobiliary surgery. With an extensive resume that includes the Royal College of Surgeons, Ireland, the prestigious Ivy League General […]

Hepatitis B and Treatment – New thoughts on old therapy for hepatitis

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Chronic hepatitis B (CHB) infection remains the most prevalent cause of liver disease in Singapore and the Asia Pacific region. Up to 40% of patients with CHB will eventually develop complications of liver failure, either from decompensation of cirrhosis or acute exacerbation of CHB (Wong and Chan 2009), or the development of hepatocellular carcinoma (HCC) […]

Hepatocellular Carcinoma

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Hepatocellular Carcinoma New therapeutic options, including liver transplantation by Dr Alfred Kow Primary liver cancer (hepatocellular carcinoma or HCC) is the fourth most common cancer in Singaporean males, with age-standardised incidence of 17.2 per 100,000 per year.1 It is twice more common in men than in women. Major risk factors for HCC include chronic liver […]

Update on Hepatitis C Therapy – The era of interferon-free treatment has begun

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Update on Hepatitis C Therapy – The era of interferon-free treatment has begun by Professor Lim Seng Gee and Dr Tan Poh Seng Hepatitis C virus (HCV) causes chronic infection in around 150 million people worldwide and accounts for more than 350,000 deaths per year.1 In Southeast Asia, HCV prevalence is estimated to be 2.15%, equivalent […]

Update on the Management of Chronic Hepatitis B Patients

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Update on the Management of Chronic Hepatitis B Patients – What is relevant for the busy general practitioner? by Dr Kelvin Thia Chronic hepatitis B infection has potential serious health consequences such as liver fibrosis, cirrhosis and hepatocellular carcinoma. In Singapore, hepatitis B seroprevalence had decreased from 4.0% in 1999 to 2.8% in 2005 with the […]

Exploring the Curable Avenues of Chronic Hepatitis C Virus

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Exploring the Curable Avenues of Chronic Hepatitis C Virus Not a Death Knell by Dr Vincent Lai Hepatitis C Virus (HCV) is a major public health problem infecting approximately 200 million people worldwide. Infection persists in 60% to 80% of patients, 25% of whom progress to cirrhosis, with the associated complication of hepatic failure and […]

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