Outwitting the Outbreaks


Professor Leo Yee Sin denies she is a perfectionist. However, those who know her beg to differ – and her long working hours are testimony to the hard work and standard of excellence she requires of herself. That means we can all breathe a little easier knowing that we are in the best hands when […]

Dengue Vaccines


Dengue fever, also aptly known as breakbone fever, is a mosquito-borne infection caused by the dengue virus, of which there are four serotypes (DENV-1 to 4). The spectrum of illness can range from a mild, non-specific febrile syndrome, to classic dengue fever (DF) with unremitting high fever, headache, muscle and joint pains, and a rash, […]

Hepatitis C


Hepatitis C Virus (HCV) is a major public health problem infecting approximately 180 million people worldwide.  Infection persists in 60% to 80% of patients, 25% of whom progress to cirrhosis with the associated complication of hepatic failure and hepatocellular carcinoma1. HCV is a virus of the flaviviridae family in the herpicivrus genus. It is an […]



I was asked to review Mr S. He was a 24-year-old Chinese man who had fever, sore throat, rash and lymphadenopathy persisting for almost a week. At consultation, he developed progressive headaches. I first met him three months prior and had diagnosed him with infectious mononucleosis. He then had a positive Epstein Barr Virus serology. […]

Human Papilloma Virus: Men do get it!


It has been well established and widely known that persistent human papilloma virus (HPV) infection causes almost all cancers and precancers of the cervix as well as genital warts in females. In addition, it is estimated to cause 40% to 50% of vulva cancers and 70% of vagina cancers. HPV types 16 and 18 cause […]

Viral Dermatoses 102


What every GP should know about papular viral dermatoses Part 1 of this article appeared in the June issue of Medical Grapevine. In this article (Part 2), common papular viral dermatoses will be discussed. There are two common papular viral dermatoses – Molluscum Contagiosum and HPV infections – which together form a substantial fraction of […]

Viral Dermatoses 101


Viral Dermatoses 101 What every GP should know by Dr Derrick Aw Viral skin diseases are very common in both the community and hospital settings. In this article, the discussion will be limited to blistering viral dermatoses (papular viral dermatoses will be discussed in a separate article). Viral exanthema will not be discussed as this […]

Community-Acquired Pneumonia in Children


Community-Acquired Pneumonia in Children Criteria for therapy and care by Dr Ratna Sridjaja Pneumonia is the single greatest cause of death in children worldwide. Each year, more than two million children younger than five years of age die from pneumonia, representing approximately 20% of all deaths in children within this age group. Community-acquired pneumonia (CAP) […]

Dengue Fever Trial in Singapore


Dengue fever trial in Singapore Dengue Bites by Dr Jenny Low Dengue is the most important arthropod-borne viral disease in human beings.1 Half of the world’s population is at risk for dengue infection. Dengue is a major cause of morbidity and mortality and a leading cause of hospitalisation among children in tropical and subtropical countries. […]

Battling Tuberculosis in the Modern World


Battling Tuberculosis in the Modern World The TB Challenge by Dr Kong Po Marn Tuberculosis (TB) is a disease that is gradual in its onset and slow in being cured. It is a significant public health problem. It is estimated that 8.8 million people developed TB and 1.4 million died from it in 2010 alone. […]

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