Systemic Sclerosis

SSc hands hi res

Current treatment measures Systemic sclerosis (SSc) is an autoimmune disease characterised by immune dysregulation, excessive fibrosis and vascular changes that can affect multiple organs. There are two subtypes: limited (LcSSc) and diffuse (DcSSc) cutaneous SSc. In LcSSc, fibrosis is mainly restricted to the fingers, hands, face, forearms (distal to the elbows) and lower legs (distal […]

Ankylosing Spondylitis


Managing an incurable condition Spondyloarthritis defines a group of diseases that have many features in common, and these include familial clustering, HLA-B27 positivity, inflammatory back pain, sacroiliitis, asymmetric peripheral arthritis, enthesitis, and extra-articular manifestations such as uveitis, inflammatory bowel disease and psoriasis. Ankylosing spondylitis (AS) is the prototype in the group, which includes psoriatic arthritis, […]

The Use of Ultrasound in Rheumatoid Arthritis

doctor studying a knee joint

Beyond conventional x-rays This article provides clinicians with an insight into the value and applicability of ultrasound (US) in Rheumatoid Arthritis (RA), and outlines the clinical scenarios which may benefit from US imaging. Management of Rheumatoid Arthritis RA is a progressive and disabling autoimmune disease characterised by inflammation of the synovial lining at the joints […]



The disease burden and management challenges Introduction Osteoarthritis (OA) of the knee is a common condition and the risk of disability attributable to knee OA alone is greater than any other medical condition among the elderly.1 The consequences of severe knee OA include loss of function and independence, and OA imposes a great economic burden […]

Systemic Lupus Erythematosus


A diagnosis not to be missed Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease which may affect the skin, joints, kidneys, lungs, heart, central nervous system and blood. It is more common in females than males with a ratio of 9:1, often affecting women of reproductive age.1 The incidence of SLE ranges from one […]

New Treatment Available for Debilitating Symptom of Rheumatoid Arthritis


One of the serious known symptoms of Rheumatoid Arthritis (RA) is morning stiffness. Traditional corticosteroid drugs, such as prednisone, are often prescribed to RA patients to treat this symptoms. However, the effect of such drugs diminish quickly and in order for patients to feel the full effects in the morning, they have to take the […]

Knees in Jeopardy – Osteoarthritis (OA)

stages of knee

Knees in Jeopardy – Osteoarthritis (OA) A Case Report Dr Yoon Kam Hon Osteoarthritis (OA) is the most common type of arthritis among over 100 different types of arthritis. In the United States alone, 27 million people are affected by OA, and 50% of US citizens have symptomatic OA knees in the course of their […]

Osteoarthritis of the Hand


Osteoarthritis of the Hand A Handful of Pain Dr Peng Yeong Pin Osteoarthritis (OA), also known as degenerative joint disease, is an entity of mechanical abnormalities involving the wear and tear of joints, resulting in cartilage degeneration, which in turn causes pain, progressive deformity and stiffness in the joint. This can happen to a traumatised […]

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